10: Costimulatory Blockade (CSB) During Mixed Lymphocyte Reaction (MLR) Prevents IL27 Upregulation and Signalling
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چکیده
منابع مشابه
Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy
BACKGROUND: It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature. Mixed lymphocyte reaction blocking antibodies are specific to the husband's lymphocytes. In the present study an attempt has been made to characterize the mixed lymphocyte reaction blocking antib...
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The results of lymphocyte functional studies performed with the peripheral blood mononuclear cells (MNCs) of patient Wa with a non-Sezary T-ceIl leukemia are described. The aggressive clinical course and the distinctive histologic, cytochemical, and cytogenetic features of this T-cell lymphoproliferative disorder are detailed in an accompanying report. Immunologic marker analysis revealed that ...
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The aggressive clinical course and the distinctive histologic, cytochemical, and cytogenetic features of an adult non-Sézary T-cell lymphoma with suppressor activity have been investigated. Morphological and ultrastructural analysis of neoplastic cells from peripheral blood and involved lymph nodes revealed cells with convoluted nuclei, prominent cytoplasmic azurophilic granules, well developed...
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Graft rejection is a manifestation of CELL-MEDIATED IMMUNITY (CMI), as can be demonstrated by adoptive transfer experiments; antibodies generally contribute little to the rejection of grafted tissues. Simple rules predict the acceptance or rejection of alloografts between inbred mice. Although these specific rules are not valid in humans (or other outbred populations), a common fundamental prin...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2008
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2007.12.018